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RuHCl(PPh3)3为主催化剂的不同催化体系能分别有效地催化1-己烯双键移动异构化和酮的氢转移还原成醇的反应.考察了反应条件(温度,时间和催化剂量)对1-己烯转化率的影响;优化结果为,在RuHCl(PPh3)3浓度为1.1×10-2mol/L(甲苯为溶剂,底物与溶剂比为4),反应温度为120℃时,在18min建立了催化平衡,得到了1-己烯的转化率为97.6%,其中2-己烯占19.3%,3-己烯占78.3%.在筛选了酮还原有效催化体系RuHCl(PPh3)3-KOH-NH2(CH2)3OH-Me2CHOH的基础上,在反应底物:RuHCl(PPh3)3:KOH:NH2(CH2)3OH为5000:1:1:1(摩尔比)下,催化不同酮底物还原为醇的产率为60%～99%;并通过IR和NMR对催化反应机理进行了初步研究.
RuHCl (PPh3) 3 as the main catalyst can effectively catalyze the isomerization of 1-hexene double bond and the hydrogen transfer reduction of ketone to alcohol, respectively. The effects of reaction conditions (temperature, time and amount of catalyst) On the conversion of 1-hexene. The optimized results showed that when the concentration of RuHCl (PPh3) 3 was 1.1 × 10-2mol / L (toluene was the solvent, the ratio of substrate to solvent was 4) and the reaction temperature was 120 ℃, The catalytic equilibrium was established at 18min, and the conversion of 1-hexene was 97.6%, of which 2-hexene was 19.3% and 3-hexene was 78.3% .After screening the effective catalyst systems for reducing ketones RuHCl (PPh3) 3 KOH: NH2 (CH2) 3OH at a molar ratio of RuHCl (PPh3) 3: KOH: NH2 (CH2) 3OH- The yield of the product reduced to alcohol was 60% -99%. The catalytic reaction mechanism was studied by IR and NMR.