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血友病是一种X连锁隐性遗传病。若男性患者与健康女性婚配,所生子女中,男孩将全都正常,女孩全都是致病基因携带者。若健康男性与致病基因携带者的女性结婚,所生子女中,1/4是女性携带者,1/4是男性血友病患者,其余都正常。人们都希望找到一种方法,在出生前就能进行判断,以便选择保留正常男孩,陶汰致病基因携带者的女孩,以预防血友病的发生。然而判断胎儿是否患有血友病是有很多困难的。最近发表了一些这方面的研究报告。这项研究工作的进展,是与以下二种技术的发展有关的。第一关于胎儿镜的使用;由于这种技术的开展,目前使血液学领域的一些疾病,如柳酸血症,镰状红细胞贫血或其他一些血红
Hemophilia is a X-linked recessive genetic disease. If a male patient is married to a healthy woman, all the children born will have normal boys and all girls will be carriers of the disease-causing genes. If a healthy male is married to a woman who is a carrier of the disease-causing gene, one fourth of the children born are women who are carriers of the carrier and one-fourth are hemophilic men. The rest are all normal. People all hope to find a way to make judgments before birth in order to choose to keep normal boys and eliminate the carriers of pathogenic genes to prevent the occurrence of hemophilia. However, there are many difficulties in judging whether a fetus has hemophilia. Recently published some research reports in this area. The progress of this research work is related to the development of the following two technologies. The first on the use of fetal mirrors; as a result of this technique, the current hematology area of some diseases, such as salicylate, sickle cell anemia or some other blood red