治疗原发性肾病综合征,最初的目的在于消除蛋白尿,并尽量维持较长时间,进而能够消豫病因,达到完全缓解。当前激素疗法虽被认为是首选疗法。但也有报告称此疗法几乎不能降低死亡率,况激素的用量、疗程各有差异而且尚无明确判断治愈的方法,往往因治疗不当而反复再发。为防止再发,大量、长期用药虽颇有效,但除了经济、精神负担外,副作用、合并症、医源性疾患的发生亦相当多。也有因此而发生后遗症及死亡者。在用激素治疗时应注意这些危险性。为提高本病缓解率,要严格规定激素治疗的标准、方法、和正确判断治疗结果。病人对激素治疗的反应性,在治疗前常难以预知,据小儿肾脏病学国际研究组制订的治疗方案,若 Treatment of primary nephrotic syndrome, the initial purpose is to eliminate proteinuria, and try to maintain a long time, and then be able to relax the cause of etiology, to achieve complete remission. Although the current hormone therapy is considered the preferred therapy. However, it has also been reported that this therapy can hardly reduce the mortality rate. The dosage of hormone, the course of treatment varies and there is no clear way to judge the cure, which is often repeated because of improper treatment. In order to prevent recurrence, a large amount of long-term medication is quite effective, but side effects, comorbidities and iatrogenic diseases are quite substantial except for economic and mental burdens. There are also sequels and deaths. In hormone therapy should pay attention to these dangers. In order to improve the remission rate of this disease, we must strictly stipulate the standard and method of hormone therapy and judge the treatment result correctly. Patients responsiveness to hormone therapy, often difficult to predict before treatment, according to Pediatric Nephrology International Study Group to develop treatment programs, if