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炭疽广泛分布于中国各地 ,特别是西部地区 ,并经常造成人畜疾病。在一项合作研究中 ,用多位点VNTR分析 (MLVA)对从 195 2～ 1998年自中国主要地理流行区域分离的病人、病畜和土壤等来源的炭疽杆菌进行了基因分型。MLVA分析结果揭示了 2 1种新的基因型 ,其等位基因组合在以前世界范围分离物的研究中未曾发现。此外 ,分离物的分群显示 ,A3b组是地理上最广泛分布的基因组 ,说明该组可能是中国的“地方流行株”。而来自古丝绸之路重要贸易中心新疆的大量分离株其基因型特别分散
Anthrax is widely distributed throughout China, especially in the western region, and often causes human and animal diseases. In a collaborative study, multi-locus VNTR analysis (MLVA) was used to genotype B. anthracis from patients, sick animals, soil and other sources isolated from major geographical areas of China from 1995-2998. MLVA analysis revealed 21 new genotypes whose allelic combinations were not found in previous studies worldwide. In addition, the segregation of isolates revealed that the A3b group was the most widely distributed in geography, indicating that the group may be “endemic” in China. A large number of isolates from Xinjiang, an important trade center of the ancient Silk Road,