IL-7是一种分子量为25KDa 的糖蛋白,对前B细胞具有刺激增殖作用,其相应cDNA已克隆化。Morrisey 等报道IL-7作为联合刺激因子通过诱导产生IL-2而刺激无辅助细胞的T 淋巴细胞的增殖。本文研究证明,IL-7和PMA 通过非依赖性IL-2途径诱导静止T 细胞合成DNA,并且使其对IL-2、IL-7和IL-4产生增殖反应。本实验用C_(57)BL/CT 和BALB/c 雌性大鼠(8～12周)获得高纯化静止T 淋巴细胞和 IL-7 is a glycoprotein with a molecular weight of 25 kDa, which stimulates the proliferation of pre-B cells. The corresponding cDNA has been cloned. Morrisey et al. Reported that IL-7 as a costimulatory factor stimulates the proliferation of T lymphocytes without helper cells by inducing the production of IL-2. The present study demonstrated that IL-7 and PMA induce quiescent T-cell DNA synthesis through a non-dependent IL-2 pathway and proliferate IL-2, IL-7 and IL-4. In this experiment, C57BL / CT and BALB / c female rats (8-12 weeks) were used to obtain highly purified resting T lymphocytes and