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目的比较持续皮下胰岛素输注(CSII)法和传统的多次皮下注射胰岛素治疗法对1型和2型糖尿病患者的短期疗效。方法糖尿病患者64例(1型糖尿病18例,2型糖尿病46例),随机分为CSII组和对照组,CSII组给予胰岛素泵持续皮下注射短效诺和灵,对照组于三餐前皮下注射短效诺和灵和睡前注射中效诺和灵。结果两组达到相同的血糖水平时,CSII组所需的治疗时间、胰岛素用量以及低血糖发生率明显减少(P<0.05)。结论胰岛素泵强化治疗能更有效地模拟生理胰岛素的分泌,更快、更有效地控制高血糖,减少血糖波动和低血糖的发生。
Objective To compare the short-term efficacy of continuous subcutaneous insulin infusion (CSII) and conventional multiple subcutaneous insulin injections in patients with type 1 and type 2 diabetes mellitus. Methods Sixty-four patients with type 1 diabetes mellitus (type 1 diabetes mellitus and 46 type 2 diabetes mellitus) were randomly divided into CSII group and control group. In CSII group, insulin pump was given to subcutaneous injection of short-acting noradrenaline, while in control group, subcutaneous injection Short-acting nocturnal and before bedtime injection promise Nexium. Results When the two groups reached the same blood glucose level, the time required for treatment, the amount of insulin and the incidence of hypoglycemia in the CSII group were significantly reduced (P <0.05). Conclusion Insulin pump intensive treatment can more effectively simulate the secretion of physiological insulin, faster and more effective control of hyperglycemia, reduce blood sugar fluctuations and hypoglycemia.