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目的:探求多发伤后多系统脏器衰竭的早期指征。方法:选择了68例因交通事故所致的胸腹联合伤病人于入院后损伤发生6h内至急诊手术后6天对中性粒细胞计数,补体C3、C4、CH50,乳酸脱氨酶,总胆红素,谷草转氨酶,肌酐,C反应蛋白诸项指标进行连续观察,并按最终是否出现多系统脏器衰竭(MSOF)分为两组,对相应的项目进行比较分析。结果:MSOF组外周血补体C3、C4和CH50明显低于非MSOF组。结论:科体系统的激活情况是早期预测MSOF的较好指标,对临床上及早干预MSOF的出现或进展可能有重要意义。
Objective: To explore the early indications of multiple system organ failure after multiple injuries. Methods: Sixty - four cases of combined thoracoabdominal and abdominal injuries caused by traffic accident were recruited within 6 hours after admission to hospital and 6 days after emergency operation. Neutrophil count, complement C3, C4, CH50, lactate deaminase, Total bilirubin, aspartate aminotransferase, creatinine and C-reactive protein were continuously observed. The patients were divided into two groups according to whether there were MSOS in the end, and the corresponding items were compared and analyzed. Results: The levels of C3, C4 and CH50 in MSOF group were significantly lower than those in non-MSOF group. Conclusion: Activation of the body system is a good indicator of early prediction of MSOF, which may be of great significance for the early onset or progression of MSOF in clinical intervention.