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目的分析研究盐酸丁咯地尔治疗糖尿病周围神经病变的临床效果。方法选取2010年8月～2012年8月我院治疗的60例糖尿病周围神经病变患者,随机分成对照组和观察组各30例,两组均采用常规降糖药物治疗,观察组加用盐酸丁咯地尔注射液;对照组加用脉络宁。治疗30d后,观察比较两组患者的治疗效果。结果观察组治疗总有效率(90.0%)显著优于对照组总有效率(76.7%),两组比较差异有显著性(P<0.05)。观察组患者的正中神经、腓总神经、尺神经、胫神经与对照组比较,均有提高(P<0.05)。治疗后,两组患者的血糖值差异无显著性(P>0.05)。结论盐酸丁咯地尔注射液治疗糖尿病周围神经病变疗效显著,副作用小,值得临床推广和应用。
Objective To study the clinical effect of buflomedil hydrochloride on diabetic peripheral neuropathy. Methods Sixty diabetic patients with diabetic peripheral neuropathy treated in our hospital from August 2010 to August 2012 were randomly divided into control group and observation group, 30 cases in each group. Both groups were treated with conventional hypoglycemic drugs. Phenol injection; control group plus Mailuoning. After 30 days of treatment, the therapeutic effect of two groups of patients was observed and compared. Results The total effective rate (90.0%) in the observation group was significantly better than that of the control group (76.7%). There was significant difference between the two groups (P <0.05). The median nerve, common peroneal nerve, ulnar nerve and tibial nerve in observation group were significantly higher than those in control group (P <0.05). After treatment, there was no significant difference in blood glucose between the two groups (P> 0.05). Conclusions Buflomedil hydrochloride injection has obvious curative effect on diabetic peripheral neuropathy with small side effects, which is worthy of clinical promotion and application.