急性热性皮肤粘膜淋巴结综合征——川崎病,是伴有一系列症状的小儿发热性疾病。1967年由川崎氏首次报告。从1970年9月至1984年9月先后四次修订了关于川崎病的诊断标准。从初版到修订后第4版虽已经历了15年的岁月,但川崎病的病因仍不明,依然是需要综合主要症状来进行诊断的一种疾病。近年来,由于应用了小儿选择性冠状动脉造影检查及二维超声装置的进展和普及,对于川崎病临床中问题最多的心血管系统障碍的研究已取得了惊人的成果。现在对川崎病的冠状动脉障碍,已不是非依靠造影在病后几个月才可诊断,而是在急性期早期,反复使用二维超声心动图观察发现冠状动脉瘤的形成而进行诊断。最近,免 Acute thermal cutaneous mucosal lymph node syndrome - Kawasaki disease, is accompanied by a series of symptoms of pediatric febrile illness. 1967 Kawasaki’s first report. From September 1970 to September 1984, the diagnostic criteria for Kawasaki disease were revised four times in succession. Although it has been 15 years since the first edition to the revised 4th edition, the cause of Kawasaki disease is still unknown and remains a disease requiring diagnosis based on the main symptoms. In recent years, due to the application of pediatric selective coronary angiography and two-dimensional ultrasound device progress and popularity of the Kawasaki disease clinical problems in the most problematic cardiovascular system has made amazing achievements. Coronary artery disease is now Kawasaki disease, is not relying on angiography in a few months after the disease can be diagnosed, but early in the acute phase, repeated use of two-dimensional echocardiography found coronary aneurysm formation and diagnosis. Recently, free