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自从最初发现ｂｃｌ２以来，它就和其它基因共同构成了一个主要影响细胞增生、生存和死亡的家庭。单一的基因突变不能导致肿瘤最后的状态，同样ｂｃｌ２的改变也遵循这一原则。ｂｃｌ２基因与家族的其它成员，以及其它癌基因、肿瘤抑制基因协同发挥作用。ｂｃｌ２的异
Since the initial discovery of bcl-2, it together with other genes has formed a family that mainly affects cell proliferation, survival, and death. A single gene mutation cannot lead to the final state of the tumor. The same bcl-2 changes also follow this principle. The bcl-2 gene and other members of the family, as well as other oncogenes, tumor suppressor genes work synergistically. Bcl-2 difference