[目的]观察康艾注射液联合放疗治疗非小细胞肺癌疗效。[方法]使用随机平行对照方法,将76例住院患者按住院病志号简单随机分为两组。对照组34例常规放射治疗,射野包括原发灶、同侧肺门、纵膈隆突下淋巴结、引流区,若病灶单一,且位于边缘,则照射病灶区及病灶外扩1.0~1.5cm区域,有明显淋巴结肿大区域,也包括在射野内6mv-X射线2ay/f DT36gy后射野避开脊髓,总剂量DT60GY~70GY。治疗组42例康艾注射液10 mL/支,40~60 mL+0.9%生理盐水,静滴,1次/d;放疗同对照组。治疗30d为1疗程。观测临床症状、T淋巴细胞亚群(CD+3 CD+4 CD+8 CD+4/CD+8)、卡式评分、不良反应(白细胞降低,体重下降,乏力改善以及伴发症状疼痛、低热、胸闷、食欲不振等)。治疗1疗程,随访四周,判定疗效。[结果]瘤体消退治疗组优于对照组(P<0.05);相关指标(体重、白细胞、乏力、生活质量,疼痛、低热、胸闷、食欲不振)治疗组改善优于对照组(P<0.05),生活质量,疼痛、低热、胸闷、食欲不振等改善两组间无明显差异(P>0.05);卡氏评分对照组明显降低(P<0.05),治疗组无明显变化(P>0.05),治疗组降低幅度低于对照组(P<0.05);T细胞亚群(CD+3CD+4 CD+8 CD+4/CD+8)治疗组无明显变化(P>0.05),对照组明显降低(P<0.01),对照组优于治疗组(P<0.01)。[结论]康艾注射液联合放疗治疗非小细胞肺癌,可明确减轻毒副作用、缓解不适症状、改善生活质量,疗效满意,值得推广。 [Objective] To observe the curative effect of Kangai injection combined with radiotherapy on non-small cell lung cancer. [Methods] Using randomized parallel control method, 76 inpatients were randomly divided into two groups according to their hospitalization pathology numbers. The control group of 34 cases of conventional radiotherapy, radiation field, including the primary tumor, ipsilateral hilar, mediastinal subgloticular lymph nodes, drainage area, if the lesion is single, and located at the edge of the irradiation lesions and lesions outside the expansion 1.0 ~ 1.5cm Area, there are obvious lymphadenopathy area, including 6mv-X ray 2ay / f DT36gy in the field after the radiation to avoid the spinal cord field, the total dose of DT60GY ~ 70GY. The treatment group 42 cases of Kang Ai injection 10 mL / branch, 40 ~ 60 mL + 0.9% saline, intravenous infusion, 1 / d; radiotherapy with the control group. Treatment for 30d for a course of treatment. Clinical symptoms, T lymphocyte subsets (CD + 3 CD + 4 CD + 8 CD + 4 / CD + 8), card score, adverse reactions (leukopenia, weight loss, improvement of fatigue and pain associated with symptoms, , Chest tightness, loss of appetite, etc.). Treatment of a course of treatment, followed up for four weeks to determine the efficacy. [Results] The tumor regression group was better than the control group (P <0.05); the improvement of the treatment group was better than that of the control group (body weight, leucocyte, fatigue, quality of life, pain, fever, chest tightness and loss of appetite) There was no significant difference between the two groups in quality of life, pain, fever, chest tightness and loss of appetite (P> 0.05). The Karnofstal score in the control group was significantly lower than that in the control group (P <0.05) (P <0.05). There was no significant change in the T cell subsets (CD + 3CD + 4 CD + 8 CD + 4 / CD + 8) compared with the control group (P <0.01), and the control group was better than the treatment group (P <0.01). [Conclusion] Kangai injection combined with radiotherapy for non-small cell lung cancer can obviously reduce the side effects, relieve the symptoms and improve the quality of life, with satisfactory curative effect and worthy of promotion.