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目的：研究癫痫亚临床发作期和发作间期脑ＳＰＥＣＴ的痫灶定位诊断价值。方法：建立亚临床发作期脑血流灌注显像方法，与间期显像对比分析定位；并结合脑ＣＴ、ＥＥＧ、ＥＣｏＧ和疗效综合评价其痫灶定位诊断价值。结果：间期ＳＰＥＣＴ阳性率、准确率、灵敏度分别为：９０．９１％、７７．２７％、８９．４７％，亚临床发作期分别为：９５．４５％、９０．９１％、１００％，优于传统定位诊断。亚临床发作期病灶放射性摄取比值也有明显增加，ＥＣｏＧ、病检阳性率１００％，远期随访有效率９０．９１％。结论：ＳＰＣＥＴ具有较高的痫灶定位诊断价值，运用亚临床发作期显像可明显提高痫灶定位阳性率、准确性和灵敏度，表明亚临床发作期ＳＰＥＣＴ安全易行，能呈现ｒＣＢＦ增加，反映出发作期的显像特征
Objective: To study the diagnostic value of epileptic foci of epileptic seizures and interictal SPECT. Methods: The method of cerebral blood flow perfusion imaging in subclinical episode was established, and compared with interphase imaging. The CT and EEG, ECoG combined with curative effect were used to evaluate the diagnostic value of focal cerebral foci. Results: The positive rate, accuracy and sensitivity of SPECT were 90.91%, 77.27% and 89.47% respectively. The rates of subclinical SPECT were 95.45%, 90.91%, 100% Better than the traditional positioning diagnosis. Subclinical lesions of the radioactive uptake ratio also increased significantly, ECoG, the positive rate of disease detection 100%, long-term follow-up effective rate of 90.91%. Conclusion: SPCET has a high diagnostic value of localization of focal epilepsy. Using subclinical seizure imaging can significantly improve the accuracy, accuracy and sensitivity of the localization of focal epilepsy, indicating that SPECT is safe and feasible in subclinical seizures and shows an increase of rCBF, reflecting Departure of the imaging features