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本文纵向观察86例糖尿病人(75例NIDDM,11例IDDM)病情控制和治疗方式对血脂水平的影响。治疗观察期平均11.3±3.8月,在此期间不服用影响脂代谢的药物。结果表明病情控制好转(53例)后TG、TC水平降低,控制差者(12例)TG、TC水平无明显改变。优降糖治疗(59例NIDDM)后HDL-C水平及HDL/LDL比值降低,胰岛素治疗(9例NIDDM,11例IDDM)后HDL-C/TC比值升高。上述血脂水平改变对糖尿病并发大血管病变的影响尚有待进一步研究。
This article longitudinal observation of 86 cases of diabetes (75 cases of NIDDM, 11 cases of IDDM) disease control and treatment of blood lipid levels. The mean duration of treatment was 11.3 ± 3.8 months, during which period no drugs that affected lipid metabolism were taken. The results showed that the control of the disease (53 cases) improved TG, TC levels decreased, poor control (12 cases) TG, TC levels did not change significantly. HDL-C and HDL / LDL decreased after glyburide treatment (59 cases of NIDDM), and HDL-C / TC ratio increased after insulin treatment (9 cases of NIDDM and 11 cases of IDDM). The above changes in blood lipid levels of diabetes complicated with macrovascular disease remains to be further studied.