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甲基强的松龙冲击疗法在治疗神经系免疫性疾病上,主要可引致消化性溃疡、易患感染、血压升高及心律失常等.文献上罕有低血钾的报道.现就本所1996年接受MPPT治疗70例患者的心电图与血钾改变作前瞻性观察,报告如下.资料与方法一、资料70例中,男41例,女29例;年龄为4~65岁(32±7.4).其中脱髓鞘性脑病22例,多发性硬化8例,急、慢性炎性脱髓鞘性多发性神经根神经病38例,面神经炎2例.二、治疗均为首次接受MPPT,其中甲基强的松龙成人用法为1g·d~(-1)(儿童按20mg·Kg~(-1)·d~(-1)),溶于5%葡萄糖液500ml中以8~10滴/min静滴,通常在12~14h滴毕,连续3日为一疗程.每天治疗前、治疗中常规查心电图示正常方可进行治疗.其中MPPT第1日或第2日起常规口服补钾,3日结束后再查血钾等电解质.
Methylprednisolone impact therapy in the treatment of neurological immune diseases, mainly can cause peptic ulcer, susceptible to infection, elevated blood pressure and arrhythmia, etc .. The literature rarely reported hypokalemia. Materials and Methods First, the data of 70 cases, 41 males and 29 females; aged 4 to 65 years (32 ± 7.4) years old, .Among them, 22 cases of demyelinating encephalopathy, 8 cases of multiple sclerosis, 38 cases of acute and chronic inflammatory demyelinating polyneuropathies and 2 cases of facial neuritis.Second, all the patients received MPPT for the first time, among them methyl Prednisolone adult use of 1g · d -1 (children press 20mg · Kg -1 d -1), dissolved in 500ml of 5% glucose solution to 8 to 10 drops / min Intravenous drip, usually in 12 ~ 14h drops completed for 3 days for a course of treatment before treatment, routine examination of ECG normal treatment before treatment.Among them MPPT on the 1st or the 2nd from the conventional oral potassium, 3 End of the day after the check potassium and other electrolytes.