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1、本文对有病史有进行性血吸虫病症状、体征(左肝>5厘米或/及脾肿大,,距末次治疗5年以上)病者按其本人愿意接受杀虫治疗与否,分为治疗组(148例)及对照组(172例)。两组分别于治后1、2及5年按治前方法复查。治后1年复查148例,有效者87例(58.8%),无变化者61例(41.2%),无1例加重。治后面部色素消失29例(70.7%),无变化者12例(29.3%),5年后随访,治疗组无1例死亡,对照组因晚血死亡者17例,占9.9%,治疗组及对照组分别于1年、2年及5年以超声波肝脾区探查复查,其结果提示肝及脾脏小2.1厘米以上者,治疗组比对照组高;而增大2.1厘米以上者则对照组高于治疗组。治疗组与对照组治后5年与治前比较,提示脾未触及率比治前高,对照组比开始时低治疗前后超声波肝脾区探查148例,其波型无明显变化。治前及治后1年复查红、白血细胞及血色素,亦无明显改变。40例于治前及治后1年分别作了血清蛋白电泳检查,均无明显改。变冶前环卵检查203例,环沉率为0、1～2、3～4及5～10%者分别为164(80.8%)、37(18.2%)、1(0.5%)及1例(0.5%)。治后1年复查69例,环沉率0、1～2、3～4、5～10%分别为63(91.3%)、4(5.8%)、2(2.9%)及0(0%)。治前139例作了间接血球凝集试验检查,阳性(1:10)者28例(20.1%)。治后1年复查20例,阳性者2例(10%),阴性者18例(90%)。2、对有病史有血吸虫病进行性症状体征病人的杀虫治疗价值作了简短的讨论。
1, this article has a history of progressive schistosomiasis symptoms, signs (left liver> 5 cm or / and splenomegaly, from the last treatment for more than 5 years) patients according to their willingness to accept insecticide treatment, divided into Treatment group (148 cases) and control group (172 cases). Two groups were treated according to pre-treatment 1,2 and 5 years respectively. One year after the treatment, 148 cases were reviewed, 87 cases (58.8%) were effective, 61 cases (41.2%) were unchanged, and none was aggravated. 29 cases (70.7%) disappeared after treatment and 12 cases (29.3%) did not change. After 5 years follow-up, there was no death in the treatment group and 17 cases (9.9%) died in the control group due to the late blood loss. The treatment group And control group at 1 year, 2 years and 5 years respectively, ultrasound liver and spleen exploration review, the results suggest that the liver and spleen of 2.1 cm or more, the treatment group than the control group; increased 2.1 cm or more in the control group Higher than the treatment group. The treatment group and the control group 5 years after treatment compared with pre-treatment, suggesting that the rate of unexplained spleen than the pre-treatment high, control group compared with the beginning of low-frequency treatment of 148 cases of liver and spleen exploration, the wave pattern did not change significantly. Review before and after treatment 1 year red, white blood cells and hemoglobin, no significant change. 40 cases of pre-and post-treatment of 1 year were made serum protein electrophoresis examination, no significant change. Totally 203 cases of anterior ovulation were enrolled, 164 (80.8%), 37 (18.2%), 1 (0.5%) and 1 (0.5%). Sixty-nine cases were retrospectively reviewed at 1 year after treatment. The rates of perineural deposition were 63 (91.3%), 4 (5.8%), 2 (2.9%) and 0 (0% . Indirect hemagglutination test was performed in 139 patients before treatment, 28 (20.1%) were positive (1:10). Twenty patients were retrospectively reviewed at 1 year after treatment, 2 (10%) were positive and 18 (90%) were negative. 2, the history of schistosomiasis patients with signs and symptoms of insecticidal treatment of the value of a brief discussion.