卵巢癌是严重威胁女性健康的恶性肿瘤之一,由于缺少有效的早期诊断方法,其死亡率一直居妇科肿瘤之首。随着对卵巢癌发病机制的深入研究,人们认识到肿瘤的发生不仅与基因突变等遗传学机制有关,也与表观遗传学异常密切相关,其中DNA甲基化是表观遗传学机制最常见的形式。本文将对D Ovarian cancer is one of the most serious malignant tumors in women. Due to the lack of effective early diagnosis, ovarian cancer has been the leading cause of gynecologic cancer. With the in-depth study of the pathogenesis of ovarian cancer, it is recognized that the occurrence of tumors is not only related to genetic mechanisms such as gene mutation, but also closely related to epigenetic abnormalities, in which DNA methylation is the most common epigenetic mechanism form. This article will be on D