本文报告21例哮喘患儿,口服氨茶碱5mg/kg/次,每日三次,测定血浆茶碱浓度为6.24～15.26μg/ml,临床效果满意,未发现毒副作用。同时指出,影响茶碱因素多,用量宜个体化,药浓监测尤为重要;药浓达有效浓度范围而疗效不佳者,应搜索原因,不宜盲目加量。 This article reports 21 cases of asthma in children, oral aminophylline 5mg / kg / times, three times a day, determination of plasma theophylline concentration of 6.24 ~ 15.26μg / ml, the clinical effect was satisfactory, no side effects were found. Also pointed out that the factors that affect the theophylline, the amount should be individualized, drug concentration monitoring is particularly important; drug concentrations of effective concentration range and poor efficacy, should search for the reasons, should not blindly increase the amount.