为观察Captopril(西德产)对精液参数和下丘脑-垂体-性腺轴的作用,在精子密度大于5×10~8/ml的精子活力不足或精于减少的58例病人中进行了双育法研究。三个月期内每日口服Captopril 50mg或等量安慰剂。初步结果显示Captopril组在精子数量方面有显著改善,说明该药对精子发生有效。因此,对激肽酶Ⅱ的抑制可能成为在治疗男子生育低 To observe the effect of Captopril on semen parameters and the hypothalamic-pituitary-gonadal axis, biweekaging was performed in 58 patients with sperm motility over or under-sperm motility greater than 5 × 10 -8 / ml Law research. Daily oral captopril 50 mg or equivalent placebo within three months. Preliminary results show a significant improvement in the number of sperm in the Captopril group, indicating that the drug is effective for spermatogenesis. Therefore, inhibition of kininase II may be a fertility-lowering treatment in men