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丹参的活血化瘀作用已有诸多报道,本文观察了丹参制剂的解痉、抗过敏等作用,并以酮替芬为阳性对照,现将实验结果报道如下。1 方法与结果1.1 丹参对整体豚鼠药物性喘息的保护作用 按文献略加更改。取体重相近的敏感豚鼠60只,均分为4组,分别灌服丹参片水溶液8g、12g生药·kg体重~(-1);酮替芬20mg·kg体重~(-1)和腹腔注射丹参注射液5g生药·kg体重~(-1)给药前后动物喘息发作潜伏期分别为丹参片水溶液小剂量组:93.1±25.8s和288.3±87.6s;大剂量组;90.4±40.2s和296.9±93.1s;丹参注射液组:92.8±31.3s和236.5±
Salvia has a lot of reports on the role of promoting blood circulation and removing blood stasis. In this paper, the effects of antispasmodic and antiallergic effects of Salvia miltiorrhiza preparations were observed, and ketotifen was taken as a positive control. The experimental results are reported as follows. 1 Methods and Results 1.1 Salvia on the overall protective effect of guinea pig drug-induced wheezing slightly modified according to the literature. Sixty sensitive guinea pigs with similar body weight were divided into 4 groups. The rats were drenched with 8g of Radix Salviae Miltiorrhizae, 12g of crude drug · kg of body weight of body weight (-1), ketotifen 20mg · kg body weight (-1) and intraperitoneal injection of Salvia miltiorrhiza The latency of asthma attack before and after administration of 5g crude drug and kg body weight (-1) were 93.1 ± 25.8s and 288.3 ± 87.6s, respectively; the high dose group was 90.4 ± 40.2s and 296.9 ± 93.1 s; Salvia miltiorrhiza injection group: 92.8 ± 31.3s and 236.5 ±