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近几十年美国前列腺癌的发病率明显增加,目前已成为美国男性患癌症死亡原因的第2位。放射疗法和手术切除是治疗前列腺癌的两种主要方法。大约有30%的病人因手术危险性大、合并症多或病灶已扩散而首选放射疗法。本文资料来源于美国1973~1990年间发病的160万癌症患者中的141 761例前列腺癌病人,其中34 889(24.9%)例首选放疗。统计疗程结束6个月后发生的膀胱癌、直肠癌、急性非淋巴细胞性白血病和慢性淋巴细胞什白血病的发病情况,并与非放疗组前列腺癌细病人进行对照研究。
The incidence of prostate cancer in the United States has increased significantly in recent decades, and it has now become the second leading cause of cancer death among men in the United States. Radiation therapy and surgical resection are the two main methods for treating prostate cancer. About 30% of patients choose radiation therapy because of the high risk of surgery, complications, or spread of the lesion. This article is based on data from 141,761 prostate cancer patients out of the 1.6 million cancer cases that occurred between 1973 and 1990 in the United States, of whom 34,889 (24.9%) were the first choice for radiotherapy. The incidence of bladder cancer, rectal cancer, acute non-lymphocytic leukemia and chronic lymphocytic leukemia occurred 6 months after the end of the statistical course of treatment, and was compared with the non-radiotherapy group.