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目的应用肝阻抗血流图及二维彩色环寻找能客观灵敏地反映脂肪肝血流动力学状态的综合指标及参数。方法在临床化验和B超检查诊断脂肪肝的基础上,应用阻抗法测定脂肪肝103例及对照组各年龄段的血流动力学指标。统计分析用均数配对t检验。结果随着脂肪肝病变程度的加重,肝血流灌注波幅(Hs)、肝血流灌注速率(Cdz/dtmax)、肝血流灌注指数[C/(B-C)]、快速射血间期(B-C)、I环和总环均逐渐降低与缩小,而门静脉、肝静脉回流阻力(Hd/Hs)、肝血流灌注阻力[(Q-B)/(B-Y)]则逐渐增大,与相应健康组对比有显著性差异(P<0.01)。结论采用Hs、Hd/Hs、Cdz/dtmax、C/(B-C)、B-C、(Q-B)/(B-Y)、I环和总环,可以客观敏感地综合反映脂肪肝的血流动力学状态。
Objective To find out the comprehensive indexes and parameters that objectively and sensitively reflect the hemodynamic status of fatty liver by using hepatic impedance blood flow diagram and two-dimensional color ring. Methods Based on clinical laboratory tests and B-ultrasound in the diagnosis of fatty liver, the hemodynamic indexes of 103 fatty liver patients and control group were determined by impedance method. Statistical analysis was paired t-test. Results With the severity of fatty liver disease, hepatic perfusion amplitude (Hs), hepatic perfusion rate (Cdz / dtmax), hepatic perfusion index [C / (B-C) (B-C), I-ring and total ring were gradually decreased and decreased, while portal vein, hepatic venous return resistance (Hd / Hs) and hepatic perfusion resistance [(Q-B) / (B-Y) Increased significantly compared with the corresponding health group (P <0.01). Conclusion Hs, Hd / Hs, Cdz / dtmax, C / B-C, B-C and B-Y can be objectively and sensitively integrated in the diagnosis of fatty liver Hemodynamic status.