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动态观察20例脑血栓形成患者急性期后及随后3周的血浆t-PA、PAI活性水平,并与正常老年人对照,以了解脑血栓形成后患者纤溶活性的变化规律,并探讨其临床意义。结果发现脑血栓形成患者血浆t-PA活性低于正常老年人(P<0.001),随后3周,PAI活性升高(P=0.059),PAI/t-PA值升高(P<0.05),纤溶功能低下并呈降低趋势
The levels of plasma t-PA and PAI in 20 patients with cerebral thrombosis after acute and 3 weeks were dynamically observed and compared with those in normal controls to understand the changes of fibrinolytic activity in patients with cerebral thrombosis, significance. The results showed that plasma t-PA activity in patients with cerebral thrombosis was lower than that in normal elderly patients (P <0.001). After 3 weeks, PAI activity increased (P = 0.059) and PAI / t- <0.05), fibrinolytic function was low and showed a decreasing trend