Purpose: In order to get deeper understanding of Diabetic Retinopathy (DR), we analyzed and evauated the results of the amplitude and latency of F-ERG a-wave, b-wave and the total amplitudes of oscillatory potentials(OPs).Methods: F-ERG of 105 eyes from 55 cases of DM were diagnosed by the medical department from July 1997 to July 1998. The 105 eyes were examined by ophthalmoscope and fluorescing in angiography and divided into there groups: 22 eyes with DM without DR(NDR), 56 eyes with background DR(BDR)and 27 eyes with proliferate DR(PDR). In addition, 30 eyes were regard as normal control group(NCG) . We used VATA-2000 type vision electrophysiological instrument and inter-national standard for clinical ERG to do measure meat and recording automatically by computer.Results: 1. The proportion of eyes number of invisible wave of a-wave, b-wave of F-ERG and Ops increased with the development of DR. 2. There were significant differences ( P< 0. 01) in the latency of a-wave between NCG and BDR and statistic Purpose: In order to get deeper understanding of Diabetic Retinopathy (DR), we analyzed and evauated the results of the amplitude and latency of F-ERG a-wave, b-wave and the total amplitudes of oscillatory potentials (OPs). Methods: F-ERG of 105 eyes from 55 cases of DM were diagnosed by the medical department from July 1997 to July 1998. The 105 eyes were examined by ophthalmoscope and fluorescing in angiography and divided into groups: 22 eyes with DM without DR (NDR) , 56 eyes with background DR (BDR) and 27 eyes with proliferate DR (PDR). In addition, 30 eyes were regard as normal control group (NCG). We used VATA-2000 type vision electrophysiological instrument and inter-national standard for clinical ERG to do measure meat and recording automatically by computer. Results: 1. The proportion of eyes number of invisible wave of a-wave, b-wave of F-ERG and Ops increased with the development of DR. 2. There were significant differences (P <0.01) in the latency of a-wave between NCG an d BDR and statistic