亚急性硬化性全脑炎(简称SSPE)是麻疹病毒引起的一种亚急性或慢性中枢神经系统疾病。1933年本病由Dawson氏首次报告。40多年来,随着病例的不断增加,对其病因、发病机理、病理变化以及临床表现等的了解也日趋深化。本文仅就上述诸问题概述如下。 Subacute sclerosing full encephalitis (SSPE) is a subacute or chronic central nervous system disorder caused by measles virus. This disease was first reported by Dawson in 1933. For more than 40 years, as the number of cases continues to increase, their understanding of the etiology, pathogenesis, pathological changes and clinical manifestations has also deepened. This article summarizes the above issues only as follows.