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1959年,Solomon和Spiro首先提出胰高糖素和高血糖之间对胃酸分泌可能有相互作用,因为联合注射胰高糖素和葡萄糖比二者分别单独注射更能使胃pH值持续升高。本文研究了健康人血糖水平与外源性胰高糖素注射后胃酸抑制效应的关系。材料与方法:8名健康志愿者,女3名,男5名,平均年令84岁。禁食一夜后,在萤光屏监视下把胃管置于胃内,排空胃液后,在150mmHg的负压下,每15分钟收集一次胃液。
In 1959, Solomon and Spiro first proposed that there may be an interaction between glucagon and hyperglycemia on gastric acid secretion, because the combination of glucagon and glucose injection alone could further increase gastric pH. This article studies the relationship between healthy people’s blood glucose levels and gastric acid suppression after exogenous glucagon injections. Materials and Methods: Eight healthy volunteers, three females, five males, with an average age of 84 years. After a fasting overnight, the tube was placed in the stomach under fluorescent screen monitoring, gastric juice was collected every 15 minutes at a negative pressure of 150 mmHg after emptying the gastric juice.