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目的探讨血液灌流联合血液透析治疗急性联苯菊酯中毒的临床疗效。方法将88例急性联苯菊酯中毒患者随机分治疗组(46例)和对照组(42例),两组患者性别、年龄、病情之间无明显差别,具有可比性。治疗组在内科常规治疗的同时给予血液灌流联合血液透析治疗,对照组仅予内科常规治疗。观察两组治疗前后临床症状缓解程度及预后。结果治疗组症状改善的时间显著短于对照组(P<0.01),差异具有统计学意义;治疗组死亡2例,对照组死亡10例。结论血液灌流联合血液透析治疗急性联苯菊酯中毒的临床疗效肯定,可短期减轻临床症状,明显改善患者预后。
Objective To investigate the clinical efficacy of hemoperfusion combined with hemodialysis in the treatment of acute bifenthrin poisoning. Methods A total of 88 patients with acute bifenthrin poisoning were randomly divided into treatment group (n = 46) and control group (n = 42). There was no significant difference between the two groups in gender, age, and disease, which were comparable. The treatment group was treated with hemoperfusion combined with hemodialysis while the conventional treatment was performed in the medical group, while the control group was given conventional therapy only. The clinical symptoms and prognosis of the two groups were observed before and after treatment. Results The symptom improvement time in the treatment group was significantly shorter than that in the control group (P <0.01), and the difference was statistically significant. Two patients died in the treatment group and 10 patients died in the control group. Conclusion Hemoperfusion and hemodialysis treatment of acute bifenthrin poisoning clinical efficacy of certain, short-term relief of clinical symptoms, significantly improve the prognosis of patients.