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为探讨中枢去甲肾上腺素（ＮＥ）能神经元兴奋对脑水肿的影响，作者观察了刺激或损毁大鼠右侧蓝斑后，同侧大脑半球脑水含量的变化．结果，ＮＥ能神经元兴奋时，同侧半球脑皮质神经元也处于兴奋状态，脑内ＮＥ，肾上腺素（Ｅ）含量分别达正常组的３０７．４６％和２９９．４１％，脑水含量（７９．２１±０．２８％）也较正常组（７８．４６±０．４２％）明显增高（Ｐ＜０．０１）．损毁蓝斑后，同侧半球脑内ＮＥ，Ｅ含量仅为正常组的１２．８０％和３２．３１％，脑水含量稍有下降，无统计学意义．提示中枢ＮＥ能神经元兴奋可能是脑水肿发生过程中的重要环节之一．
To investigate the effect of central noradrenaline (NE) neurons excitability on brain edema, the authors observed changes in brain water content in the ipsilateral cerebral hemispheres after stimulating or damaging the right plaque of rats. As a result, the NE neurons in the ipsilateral hemisphere were also excited at the time of NE neuron excitation. The levels of NE and epinephrine in the brain reached 307.46% and 299.41% respectively in the normal group. The brain water content ( 79.21 ± 0.28%) than the normal group (78.46 ± 0.42%) (P <0.01). Damage to the blue plaque, the ipsilateral hemispheric NE, E content was only 12.80% and 32.31% of the normal group, a slight decrease in brain water content, without statistical significance. It is suggested that the excitability of NE neurons in the central nervous system may be one of the important links in the process of brain edema.