Focus on face-centered cubic(fcc)metals with nano-scale twins lamellar structure,this paper presents a brief overview of the recent progress made in improving mechanical properties,including strength,ductility,work hardening,strain rate sensitivities,and in mechanistically understanding the underling deformation mecha- nisms.Significant developments have been achieved in nano-twinned fcc metals with a combination of high strength and considerable ductility at the same time,enhanced work hardening ability and enhanced rate sensitivity.The findings elucidate the role of interactions between dislocations and twin boundaries(TBs)and their contribution to the origin of outstanding properties.The computer simulation analysis accounts for high plastic anisotropy and rate sensitivity anisotropy by treating TBs as internal interfaces and allowing special slip geometry arrangements that involve soft and hard modes of deformation.Parallel to the novel mechanical behaviors of the nano-twinned materials,the investigation and developments of nanocrystalline materials are also discussed in this overview for comparing the contribution of grain boundaries/TBs and grain size/twin lamellar spacing to the properties.The recent advances in the experimental and computational studies of plastic deformation of the fcc metals with nano-scale twin lamellar structures provide insights into the possible means of optimizing comprehensive mechanical properties through interfacial engineering. Focus on face-centered cubic (fcc) metals with nano-scale twins lamellar structure, this paper presents a brief overview of the recent progress made in improving mechanical properties, including strength, ductility, work hardening, strain rate sensitivities, and in mechanistically understanding the underling deformation mecha- nisms. Significant developments have been achieved in nano-twinned fcc metals with a combination of high strength and considerable ductility at the same time, enhanced work hardening ability and enhanced rate sensitivity. The findings elucidate the role of interactions between dislocations and twin to twin (TBs) and their contribution to the origin of outstanding properties. The computer simulation analysis accounts for high plastic anisotropy and rate sensitivity anisotropy by treating TBs as internal interfaces and allowing special slip geometry arrangements that involve soft and hard modes of deformation. Parallel to the novel mechanical behaviors of the nano-twinned mate rials, the investigation and developments of nanocrystalline materials are also discussed in this overview for comparing the contribution of grain boundaries / TBs and grain size / twin lamellar spacing to the properties. recent recent in the experimental and computational studies of plastic deformation of the fcc metals with nano-scale twin lamellar structures provide insights into the possible means of optimizing comprehensive mechanical properties through interfacial engineering.