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[目的]观察正清风痛宁联合西药治疗类风湿性关节炎疗效。[方法]使用随机平行对照方法,将56例住院患者按就诊顺序号简单随机分为两组。对照组28例强的松5~10mg/次,1次/d;柳氮磺吡啶1g/次,2次/d;甲氨蝶呤10mg/次,1次/周;服用甲氨蝶呤第二天服用叶酸10mg。治疗组28例正清风痛宁缓释片60mg/次,2次/d;西药治疗同对照组。连续治疗90d为1疗程。观测临床症状、晨僵时间、关节肿痛、关节功能、血沉、类风湿因子、不良反应。治疗1疗程,判定疗效。[结果]治疗组临床控制11例,显效9例,有效6例,无效2例,总有效率92.86%。对照组临床控制6例,显效8例,有效5例,无效9例,总有效率67.86%。治疗组疗效优于对照组(P<0.05)。晨僵时间两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]正清风痛宁联合西药治疗类风湿性关节炎疗效满意,无副作用,值得推广。
[Objective] To observe the effect of Zhengqingfengtongning combined with Western medicine in treating rheumatoid arthritis. [Methods] Using randomized parallel control method, 56 cases of inpatients were randomly divided into two groups according to the order of visiting doctor. The control group 28 cases of prednisone 5 ~ 10mg / time, 1 / d; sulfasalazine 1g / times, 2 times / d; methotrexate 10mg / times, 1 / week; taking methotrexate Take folic acid 10mg two days. 28 cases of treatment group is Qingfengtongning sustained release tablets 60mg / time, 2 times / d; Western medicine treatment with the control group. Continuous treatment of 90d for a course of treatment. Observation of clinical symptoms, morning stiffness time, joint swelling and pain, joint function, ESR, rheumatoid factor, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] In the treatment group, 11 cases were clinically controlled, 9 cases markedly effective, 6 effective and 2 ineffective, with a total effective rate of 92.86%. Control group, 6 cases of clinical control, markedly effective in 8 cases, effective in 5 cases, ineffective in 9 cases, the total effective rate was 67.86%. The treatment group was better than the control group (P <0.05). Morning stiffness increased in both groups (P <0.01), and the treatment group improved better than the control group (P <0.01). [Conclusion] Zhengqing Fengtongning combined with Western medicine has satisfactory curative effect on rheumatoid arthritis without side effect and is worth popularizing.