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Reviewing the history of the development of artificial intelligence (AI) clearly reveals that brain science has resulted in breakthroughs in AI,such as deep leing.At present,although the developmental trend in AI and its applications has surpassed expectations,an insurmountable gap remains between AI and human intelligence.It is urgent to establish a bridge between brain science and AI research,including a link from brain science to AI,and a connection from knowing the brain to simulating the brain.The first steps toward this goal are to explore the secrets of brain science by studying new brain-imaging technology;to establish a dynamic connection diagram of the brain;and to integrate neuroscience experiments with theory,models,and statistics.Based on these steps,a new generation of AI theory and methods can be studied,and a subversive model and working mode from machine perception and leing to machine thinking and decision-making can be established.This article discusses the opportunities and challenges of adapting brain science to AI.