随着对慢性阻塞性肺疾患(COPD)及支气管哮喘的发病机制的进一步探讨,当前,对平喘药的药理及药物血浓度也有深一步的研究。氨茶硷是一个有效的支气管平滑肌舒张药,临床主要用于支气管哮喘和喘息型慢性支气管炎,但它的治疗指数窄,个体差异大,使用常感困难。为配合临床更好地合理用药,我们测定了5例COPD患者使用氨茶硷后的药动学参数,并由此预测病人服药后的血药浓度,找 With the further study on the pathogenesis of chronic obstructive pulmonary disease (COPD) and bronchial asthma, there is a further study on pharmacology and drug blood concentration of antiasthmatic drugs. Theophylline is an effective bronchial smooth muscle diastolic drug, clinical mainly for bronchial asthma and asthmatic chronic bronchitis, but its therapeutic index is narrow, individual differences, the use of often difficult. In line with the clinical rational use of drugs, we measured the 5 patients with COPD patients after using aminophylline pharmacokinetic parameters, and thus predict the patient’s blood concentration after taking medicine, find