有关骨巨细胞瘤性质的问题,自Cooper(1918)首次描述后,60多年来一直存有争议。该氏认为系一髓腔内恶性肿瘤,主张截肢。但不久,Bloodgood指出其良性特点,并强调用较保守的手术治疗。1940年jaffe等按组织学将其分为三级,即Ⅰ级(属良性),Ⅱ级(中间型),Ⅲ级(属恶性)。60年代初期,很多学者对这一肿瘤的良性性质提出了异议,如Jawell则称其为所谓“良性”。方先之等(1960)为避免给人一种假安全感,则不主 Questions about the nature of giant cell tumors have been debated for more than 60 years since Cooper (1918) first described them. The think of a Department of intramedullary malignant tumor, advocating amputation. But shortly after, Bloodgood pointed out its benign features and emphasized the use of more conservative surgeries. In 1940 jaffe, etc. according to histology will be divided into three levels, namely Ⅰ (benign), Ⅱ (intermediate), Ⅲ (malignant). In the early 1960s, many scholars raised objections to the benign nature of this tumor, as Jawell called it “benign.” Fang Xianzhi, etc. (1960) To avoid giving a false sense of security, not the main