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１５例肝细胞癌与５例胚肝的超微结构比较，两者相似之处是均具有核位于中心的多边形细胞，粗面内质同及线粒体丰富，板层状的粗面内质网，有胆小管及窦周隙形成，这对电镜观察确定肿瘤的肝细胞源性有重要意义；也可看到两者明显差别，如癌细胞的多型性、异质性、超微结构成分的不同步分化、以及浸润性生长．这提供了在电镜下判断一个恶性肿瘤的依据。在肝细胞癌中，看到２０个单个性死癌细胞，有核固缩，虽无凋落小体形成，我们仍考虑这些细胞属凋落性死亡。在过半病例中看到由Ｔ－淋巴细胞或大颗粒淋巴细胞导致的癌细胞灶性破坏。
Compared with the ultrastructure of 15 cases of hepatocellular carcinoma and 5 cases of embryonic liver, the similarities between them are polygonal cells with nucleus located at the center, rough endoplasm with rich mitochondria, lamellar rough endoplasmic reticulum, There are bile ducts and peri-sinusoidal space formation, which is important for electron microscopic observation and determination of the hepatocyte-derived nature of tumors; obvious differences can also be seen, such as the polymorphism, heterogeneity, and ultrastructural components of cancer cells. Asynchronous differentiation and invasive growth. This provides the basis for judging a malignant tumor under electron microscope. In hepatocellular carcinoma, 20 individual dead cancer cells are seen, with nuclear pyknosis, and although there is no litter body formation, we still consider these cells to be associated with litter death. Over half of the cases saw focal destruction of cancer cells caused by T-lymphocytes or large granular lymphocytes.