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25和50ppm的苯可使小鼠的脾脏和胸腺重量明显降低;外周血T淋巴细胞数明显减少;迟发型变态反应受到抑制;小鼠足垫肿胀部位单核细胞浸润明显少于对照组。15ppm苯即可引起T淋巴细胞数下降。提示苯是一种免疫抑制剂。
25 and 50ppm of benzene can significantly reduce the weight of mice spleen and thymus; peripheral blood T lymphocytes was significantly reduced; delayed type allergy was inhibited; mouse foot pad swollen monocyte infiltration was significantly less than the control group. 15ppm benzene can cause T lymphocytes decreased. Benzene is an immunosuppressive agent.