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慢性炎症性脱髓鞘多发性神经根神经病(CID-PN)与急性格林巴利不同,也与遗传疾病、骨髓瘤、白血病、淋巴瘤、癌、糖尿病和肝病等所致的多发性神经根神经病不同。本病隐袭起病,逐渐加重,有无力和感觉障碍,肢体近端和远端对称性受累。CSF 中无或极少淋巴细胞,蛋白升高。有神经传导和肌电异常。CIDPN 病因不明,从其表现与格林巴利和实验性变态反应神经炎相似,推测发病与体液免疫有关。作者用血浆交换治疗CIDPN29例,用前瞻性双盲随机试验研究。血浆交换组15例,假交换(Shame exchange)14例作为对照组,14例中11例假交换后又行血浆交换。用间断或连续血细胞分
Chronic inflammatory demyelinating polyradiculoneuropathy (CID-PN), unlike acute gribbali, is also associated with multiple neuropathic neuropathies resulting from genetic diseases, myeloma, leukemias, lymphomas, cancers, diabetes and liver diseases different. Insidious onset of this disease, and gradually increased, weakness and sensory disturbance, limb proximal and distal symmetry involvement. No or very few lymphocytes in CSF with elevated protein. There are nerve conduction and EMG abnormalities. CIDPN etiology is unknown, from its performance and the Greenbalin and experimental allergic neuritis similar to the speculation that the incidence of humoral immunity. The authors used plasma exchange treatment of CIDPN29 cases, a prospective, double-blind randomized study. There were 15 cases of plasma exchange group and 14 cases of shame exchange as control group. Of the 14 cases, 11 cases were exchanging for plasma exchange after sham exchange. With intermittent or continuous blood cell points