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近年,已经证明高胰岛素血症和胰岛素耐受是多囊卵巢综合征(PCOS)的重要特征。高雄激素血症是由于胰岛素和/或胰岛素样生长因子1(IGF-1)对卵巢直接作用增强所致。高胰岛素血症也可以由于肝脏分泌的胰岛素样生长因子结合蛋白-1(IGFBP-1)减
In recent years, hyperinsulinemia and insulin resistance have proven to be important features of polycystic ovary syndrome (PCOS). Hyperandrogenism is caused by a direct effect of insulin and / or insulin-like growth factor 1 (IGF-1) on the ovary. Hyperinsulinemia may also be due to the hepatic secretion of insulin-like growth factor binding protein-1 (IGFBP-1) minus