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右旋糖酐40是蔗糖经肠膜状串珠菌L.M-1226发酵后生成的高分子葡萄糖聚合物,平均分子量40 000。临床上可用于防治休克和缺血性血管疾病,预防术后静脉血栓形成,对血管栓塞性疾病亦有疗效。其不良反应时有报道,严重者导致休克甚至死亡。本文对使用右旋糖酐40葡萄糖注射液致严重过敏性休克的病例进行分析,提出风险防范措施,为临床安全用药提供参考。1病例报告患者,男,60岁,因左第1、2、3、4跖骨开放性粉碎性骨折,
Dextran 40 is a polymer of glucose polymers produced by the fermentation of sucrose by S. enteritidis L.M-1226 and has an average molecular weight of 40,000. Clinically available for the prevention and treatment of shock and ischemic vascular disease, prevention of postoperative venous thrombosis, vascular embolic disease is also effective. Adverse reactions are reported, severe cases lead to shock or even death. In this paper, the use of dextran 40 glucose injection of severe cases of anaphylactic shock were analyzed, the risk prevention measures to provide a reference for clinical safety medication. 1 case report patients, male, 60 years old, because the left 1,2,3,4 metatarsal open comminuted fracture,