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1986～1987年在海南岛乐东县和崖县应用世界卫生组织推荐的体外微最法继续监视恶性疟原虫对氯喹、喹(口派)氨酚喹、甲氟喹和奎宁的敏感性。喹(口派)测定板由我们制作,其它4种药物测定板由世界卫生组织供应。 氯喹、喹哌、氨酚喹、甲氟喹和奎宁分别在≥1.14、6.4、0.2、3.2、25.6×10~-6mol/L药物井中疟原虫仍能发育成裂殖体时为对该种药物存在抗药性。 一、测定氯喹96例,抗性55例,抗性率57.3％,
From 1986 to 1987, the sensitivity of Plasmodium falciparum to chloroquine, quinine (oral) paracetamol, mefloquine and quinine continued to be monitored by the micro-sumaca method recommended by the World Health Organization in Ledong County and Yanya County, Hainan Island. Quiz (Mouth) assay plates were made by us and the other four drug assay plates were supplied by the World Health Organization. Chloroquine, quinpirole, paracetamol, mefloquine and quinine in the ≥ 1.14,6.4,0.2,3.2,25.6 × 10 ~ -6mol / L drug wells in malaria parasite can still develop into schizonts when the species Drug resistance. First, the determination of chloroquine 96 cases, 55 cases of resistance, resistance rate of 57.3%