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电容成像技术在皮肤测量领域中具有非常大的潜力.皮肤水分测试仪(Corneometer)是当前皮肤测量中应用最为广泛的基于电容接触测量原理的仪器之一,但是其重复性较差,无法校准,并且不具备成像功能.本文研究开发了一种新型无损伤的基于电容接触成像技术的仪器:艾普西龙皮肤水分测试成像系统(Epsilon),与Corneometer相比,Epsilon具有可成像、重复性好和可校准的优势,并能对皮肤损伤所形成的随时间变化的曲线,以及溶液渗透状况进行分析.文章通过3个实验来研究电容接触成像技术在皮肤测量中的应用:(1)Epsilon和Corneometer精确度和重复性的实验分析;(2)皮肤损伤特征分析:深度洗涤,发泡剂(SLS)刺激,以及胶带剥离实验;(3)体外猪皮溶液渗透的实验分析.结果显示,Epsilon与Corneometer相比,具有更好的重复性和精确度,通过Epsilon测量所产生的图像可以直观地观察皮肤水化以及溶液渗透皮肤的状况,其测量结果形成的随时间变化的曲线可以反映出皮肤损伤和溶液渗透的程度,通过不同形状的闭合曲线可以判断出皮肤损伤的方式,而通过校准后仪器测量出的介电常数,可以计算出皮肤中准确的水化含量,从而进行更进一步的分析.
Capacitance imaging has great potential in the field of skin measurement.Corneometer is one of the most widely used instruments based on the principle of capacitive contact measurement in current skin measurement but its repeatability is poor and can not be calibrated, And does not have imaging capabilities.In this paper, we developed a new nondestructive instrument based on capacitive contact imaging technology: Epsilon skin imaging test system (Epsilon), compared with the Corneometer, Epsilon has good imaging and repeatability And calibratable advantages and can analyze the curve of skin lesions over time and the state of solution penetration.Through three experiments to study the application of capacitive contact imaging in skin measurement: (1) Epsilon and Corneometer Accuracy and repeatability of the experimental analysis; (2) analysis of the characteristics of the skin lesions: depth washing, blowing agent (SLS) stimulation and tape stripping experiments; (3) in vitro pig skin solution penetration experimental results show that Epsilon With better repeatability and accuracy than the Corneometer, images generated by Epsilon measurements allow visual observation of skin hydration and Fluid penetration through the skin, the measurement of the formation of the curve over time can reflect the degree of skin damage and solution penetration through the closed curve of different shapes can determine the way the skin damage, and through the instrument after the calibration of the measured medium Electric constant, can calculate the accurate hydration of the skin content for further analysis.