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目的探讨特比萘芬(Terbinafine)联合派瑞松霜(PevisoneCream)治疗念珠菌性包皮龟头炎的临床疗效及安全性。方法选择确诊患者95例,随机分为两组,治疗组50例,采用特比萘芬250mg顿服,每天1次,连服2周,同时给予派瑞松霜外涂,每天早晚各1次,连用2周;对照组45例,单纯给予派瑞松霜外涂,用法及疗程同治疗组;停药2周后复诊观察疗效及真菌清除率。结果治疗组痊愈30例,占60%,对照组治愈17例,占38%;两组治愈率比较,差异有显著性(χ2=4.679,P<0.05);治疗组有效45例,占90%,对照组有效33例,占73%;两组有效率比较,差异有显著性(χ2=4.478,P<0.05);两组均无明显不良反应。结论特比萘芬联合派瑞松霜治疗念球菌性包皮头炎的效果确切、痊愈率高,且副反应少。
Objective To investigate the clinical efficacy and safety of Terbinafine combined with Pevisone Cream in the treatment of candidal foresch balanitis. Methods Selected 95 cases of patients diagnosed randomly divided into two groups, the treatment group of 50 cases, the use of terbinafine 250mg Dayton clothing, day 1, and even for 2 weeks, while giving perelaxan cream coating, morning and evening 1 time each day, For 2 weeks; control group of 45 cases, were given Pessimist cream cream alone, usage and course of treatment with the treatment group; withdrawal two weeks after the visit to observe the efficacy and fungal clearance rate. Results The treatment group cured 30 cases, accounting for 60%, the control group cured 17 cases, accounting for 38%; two groups of cure rates, the difference was significant (χ2 = 4.679, P <0.05) , 33 cases were effective in the control group, accounting for 73%. There was significant difference between the two groups (χ2 = 4.478, P <0.05). There was no obvious adverse reaction in both groups. Conclusion Terbinafine combined with pirosonide treatment of Candidiasis foreskin inflammation effect is exact, high cure rate, and fewer side effects.