白细胞介素1β(Interleukine IL-1β)是一种在免疫应答、炎症反应中起重要作用的细胞因子。近年,细胞生物学的研究发现,IL-1β等细胞因子与尖周病、牙周病的发病有一定关系。本文就IL-1β的主要特性(产生IL-1的细胞和诱导物、IL-1的结构和受体、IL-1的主要作用)和IL-1β与尖周病、牙周病的关系(IL-1β与尖周病、牙周病的主要致病菌、IL-1β与尖周病、牙周病的临床症状)方面进行初步阐述。 Interleukin IL-1β is a cytokine that plays an important role in immune response and inflammation. In recent years, the study of cell biology found that IL-1β and other cytokines and periodontal disease, periodontal disease have a certain relationship. In this paper, the main characteristics of IL-1β (IL-1-producing cells and inducers, IL-1 structure and receptor, the main role of IL-1) and IL-1β and apical and periodontal disease IL-1β and apical disease, the main pathogens of periodontal disease, IL-1β and apical disease, clinical symptoms of periodontal disease) were initially described.