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目的探讨血管内介入栓塞疗法对脑血管畸形的治疗效果。方法选择2011年1月至2014年7月收治的脑血管畸形患者74例,以数字法随机分为治疗组和对照组,每组37例。治疗组采用血管内介入栓塞疗法治疗,对照组在显微镜下进行直接切除处理。对比两组治疗效果,并在治疗6个月后进行随访。结果治疗组手术时间及出血量均显著低于对照组,治疗组有效率为97.30%(36/37),显著高于对照组的81.08%(30/37)。随访结果中治疗组存活率为97.30%(36/37),高于对照组的81.08%(30/37),出现脑出血、脑血管痉挛等病患比例均显著低于对照组。治疗组ALD评分达到ADLⅠ、ADLⅡ级的比例显著高于对照组,而ADLⅣ、ADLⅤ级比例低于对照组,差异均有统计学意义(P均<0.05)。结论采用血管内介入栓塞疗法治疗脑血管畸形疾病能有效减少手术中对患者的创伤,且治疗效果明显。在治疗后出现的并发症概率低、存活率高,有效保证患者治疗后的生活水平。
Objective To investigate the therapeutic effect of endovascular embolization on cerebrovascular malformations. Methods Totally 74 patients with cerebrovascular malformations who were admitted from January 2011 to July 2014 were randomly divided into treatment group and control group by digital method, with 37 cases in each group. The treatment group was treated with endovascular interventional embolization, and the control group underwent direct resection under the microscope. The therapeutic effects of two groups were compared and followed up for 6 months. Results The operation time and bleeding amount in the treatment group were significantly lower than those in the control group. The effective rate was 97.30% (36/37) in the treatment group, which was significantly higher than that in the control group (81.08%, 30/37). The follow-up results of the treatment group survival rate was 97.30% (36/37), 81.08% (30/37) higher than the control group, the occurrence of cerebral hemorrhage, cerebral vasospasm and other patients were significantly lower than the control group. ALD score of the treatment group reached ADL Ⅰ, ADL Ⅱ level was significantly higher than the control group, while ADL Ⅳ, ADL V level lower than the control group, the difference was statistically significant (P all <0.05). Conclusions The treatment of cerebrovascular malformation by endovascular interventional embolization can effectively reduce the trauma to patients during operation, and the curative effect is obvious. The probability of complications after treatment is low, and the survival rate is high, effectively guaranteeing the living standard after treatment.