例1,男,54岁.诊断为闭合性股骨骨折,入院第七天出现患肢阵发性不自主抽搐,用止疼剂无效,抽搐渐重,又加大牵引重量,以期对抗肌肉强烈收缩,仍无济于事.5天后出现苦笑面容和张口困难,方诊断为破伤风而给以相应治疗.发病后第八天窒息死亡.经追问病史,得知20年前右大腿曾被铁钉刺伤,刺孔很快自行愈合. Case 1, male, 54 years old. Diagnosis of closed femoral fractures, admission on the seventh day of paroxysmal involuntary involuntary limbs, with painkillers invalid, twitching heavier, but also increase the traction weight, in order to combat muscle contraction , Still no good .5 days after the smile face and mouth difficulties, the diagnosis of tetanus side to give the appropriate treatment .8 days after the onset of suffocation death.Has asked history, that 20 years ago the right thigh had been stabbed by a nail, Prickles quickly heal themselves.