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宫颈癌与高危型人乳头状瘤病毒(HPV)的持续感染密切相关[1],P16INK4A基因产物在HPV感染引起的宫颈癌多步骤、多阶段病变中起重要作用[2],我们检测了2005年6月至2008年3月送检的284例宫颈组织标本中HPV16/18感染和P16INK4A蛋白表达的情况,分析两者的关系,报告如下。对象与方法1.
Cervical cancer is closely related to persistent infection of high-risk human papillomavirus (HPV) [1]. P16INK4A gene product plays an important role in multi-stage and multi-stage cervical cancer caused by HPV infection. [2] HPV16 / 18 infection and P16INK4A protein expression in 284 cases of cervical tissue examined from June to March 2008 were analyzed. The relationship between the two was analyzed as follows. Objects and methods 1.