支气管反应增强是支气管哮喘的一个特征,并常作为此病的诊断依据,有关机制尚不明了。据认为,迷走神经反射亢进和(或)缺乏β-肾上腺受体应答是很重要的。早些时候,Malik 等氏的实验证实麻风患者对刺激性气溶胶的反射性咳嗽次数减少,且呼吸反射延长,这使我们相信麻风是“迷走神经活性减弱的一个临床模型”。 Bronchial hyperresponsiveness is a hallmark of bronchial asthma and often serves as a basis for the diagnosis of the disease, and the mechanism is not known. It is considered important that vagal reflexes and / or lack of β-adrenergic receptor responses. Earlier, experiments by Malik et al. Confirmed that patients with leprosy had fewer reflex coughs on irritating aerosols and prolonged respiratory reflexes, which led us to believe that leprosy is “a clinical model of diminished vagal activity.”