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采用放射免疫法测定了21例肝肾功能正常的EH患者和19例正常人血浆PTH-M浓度。结果显示,FH患者血浆PTA-M浓度明显高于正常人(192.27±71.44比136.44±85.14pg/ml,P<0.05),两组受检者血浆PTH-M浓度均与MAP呈正相关,EH患者血浆PTH-M浓度与PRA呈负相关。提示甲状旁腺素或与其分泌有关的物质可能参与血压调节,甲状分腺机能亢进在EH特别是低肾素型EH发病机理中可能具有一定病理意义。
Radioimmunoassay was used to determine the plasma concentrations of PTH-M in 21 EH patients with normal liver and kidney function and 19 normal controls. The results showed that plasma PTA-M concentrations in patients with FH were significantly higher than those in normal controls (192.27 ± 71.44 vs 136.44 ± 85.14pg / ml, P <0.05). Plasma PTH-M concentrations in both groups were positively correlated with MAP, Plasma PTH-M concentration was negatively correlated with PRA. Suggesting that parathyroid hormone or its secretion-related substances may be involved in blood pressure regulation, thyroid gland hyperfunction in EH especially low-renin EH pathogenesis may have some pathological significance.