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疫苗拯救了无数生命,但偶尔出现婴儿猝死综合征(SIDS),尽管一般的流行病学研究并未在接种与SIDS之间显示出正性关联.然而,当多次SIDS报告都一致判定不良事件系源于一批疫苗时,理论上是应考虑个别一批产品可能起到病原作用(虽然严格的质量控制程序在正常情况下能保证每批投放市场的疫苗是安全有效的,但多批疫苗之间,其成份也可能存在较小的差异).为了评估美国疫苗不良事件报告系统(VAERS)中众多SIDS死亡报告的差异,作者估计了3a中白百破混合制剂(DTP)免疫后仅2d内SID死亡分布情况.
The vaccine saved innumerable lives, but occasionally Sudden Infant Death Syndrome (SIDS), although general epidemiological studies did not show a positive association between vaccination and SIDS. However, when multiple SIDS reports consistently agreed that adverse events When originating from a group of vaccines, it is theoretically possible that individual batches of products may be considered pathogenic (although stringent quality control procedures can normally and safely ensure that each batch marketed is safe and effective, multiple batches of vaccine There may be minor differences in their composition.) To assess differences in the number of SIDS deaths reported in the VAERS, the authors estimated that after 2-D immunization with DTP (3a) Distribution of internal SID deaths.