据报道感染恶性疟原虫滋养体的红细胞膜表面引起的结节含有某种抗原物质,并与红细胞附着于后毛细静脉内膜有关。恶性疟原虫在长期体外培养过程中,会发生突变,形成新的克隆,这些克隆感染的红细胞表面不再形成结节。疟原虫的这一变化,使其更适应于体外的生长繁殖,但对于体内生长是否有利呢?本文作者用冈比亚FCR-3恶性疟原 It is reported that the nodules caused by the surface of the erythrocyte membrane infected with P. falciparum trophozoites contain some antigenic substance and are involved in the attachment of erythrocytes to the posterior capillary vein. Plasmodium falciparum in the long-term in vitro culture process, mutation occurs, the formation of new clones, these clones infected erythrocyte surface no longer nodules. This change in Plasmodium makes it more suitable for in vitro growth and reproduction, but is it beneficial for in vivo growth? The authors used the Gambian FCR-3 Plasmodium falciparum