由于乙型肝炎抗原(HB sAg)的发现近年来,有关原发性肝癌和乙型肝炎关系的文献日益增多。有的认为,乙型肝炎可能是肝癌的一种病因,也有的认为两者可能只是相伴随,不一定有因果关系。但多数文献指出,原发性肝癌和乙型肝炎的关系是十分密切的。随着HB sAg检测灵敏度的增加,肝癌中HBsAg的阳性率也明显上升,有达80%以上者,远高于正常人群。本文根据我们1975年以来的工作,探索两者的关系。 Due to the discovery of hepatitis B antigen (HB sAg) in recent years, the literature on the relationship between primary liver cancer and hepatitis B is increasing. Some people believe that hepatitis B may be a cause of liver cancer, and some think that the two may only be concomitant, not necessarily a causal relationship. However, most literature points out that the relationship between primary liver cancer and hepatitis B is very close. With the increase of the detection sensitivity of HB sAg, the positive rate of HBsAg in liver cancer has also increased significantly, reaching over 80%, which is much higher than the normal population. This article explores the relationship between the two, based on our work since 1975.