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采用荧光分光光度法测定了小鼠组织和血清中丙二醛的含量变化。①3.0 Gy照射后12—24h时,丙二醛含量最高,随后逐渐下降;②不同剂量(0—4.0 Gy)照射后24h时,丙二醛含量和照射剂量呈正相关,即丙二醛的含量可很好地反映出机体的损伤情况;③Vit E对辐照后小鼠氧化损伤具有保护作用,250μg/g重体的Vit E用量是抗氧化作用的最佳用量。
Fluorescence spectrophotometry was used to determine the content of malondialdehyde in mouse tissues and serum. ①The content of malondialdehyde was the highest at 12-24h after 3.0 Gy irradiation and then decreased gradually. ② The content of malondialdehyde was positively correlated with the dose at 24 h after irradiation (0-4.0 Gy) Content can well reflect the damage of the body; Vit E has a protective effect on oxidative damage of irradiated mice, and the dosage of Vit E at 250 μg / g body weight is the best dosage of anti-oxidation.